![]() However, it has a bitter taste, so early formulations of tonic water also contained large amounts of sugar to make it more palatable. The active ingredient in tonic water, quinine, is an effective antimalarial agent. Tonic water first appeared in the 18th century as a medicinal remedy to prevent malaria. Some brands also add sodium benzoate or potassium sorbate as preservatives. Gain weight by “going diet?” Artificial sweeteners and the neurobiology of sugar cravings.While the ingredients can vary depending on the brand, most tonics contain sugar, quinine, citric acid, and natural flavoring agents. ![]() Beverages, carbonated, SPRITE, lemon-lime, without caffeine. A dose-response study of consuming high-fructose corn syrup–sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults. Does diet-beverage intake affect dietary consumption patterns? Results from the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. Long-term consumption of sugar-sweetened and artificially sweetened beverages and risk of mortality in US adults. Associations between brain structure and perceived intensity of sweet and bitter tastes. Scientific opinion on the re‐evaluation of aspartame (E 951) as a food additive.
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